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Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos

VEGFA signaling controls physiological and pathological angiogenesis and hematopoiesis. Although many context-dependent signaling pathways downstream of VEGFA have been uncovered, vegfa transcriptional regulation in vivo remains unclear. Here, we show that the ETS transcription factor, Etv6, positiv...

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Detalles Bibliográficos
Autores principales: Li, Lei, Rispoli, Rossella, Patient, Roger, Ciau-Uitz, Aldo, Porcher, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403364/
https://www.ncbi.nlm.nih.gov/pubmed/30842454
http://dx.doi.org/10.1038/s41467-019-09050-y