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B-cell translocation gene 2 enhances fibroblast growth factor 21 production by inducing Kruppel-like factor 15

Fibroblast growth factor 21 (FGF21) is a hormone that is vital for the regulation of metabolic homeostasis. In the present study, we report that Kruppel-like factor 15 (KLF15) is a novel mediator of b-cell translocation gene 2 (BTG2)-induced FGF21 biosynthesis. The expression levels of hepatic Fgf21...

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Detalles Bibliográficos
Autores principales: Kim, Yong Deuk, Hwang, Seung-Lark, Jeon, Hwang-Ju, Jeon, Yong Hyun, Nedumaran, Balachandar, Kim, Kyeongsoon, Lee, Sung-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403367/
https://www.ncbi.nlm.nih.gov/pubmed/30842568
http://dx.doi.org/10.1038/s41598-019-40359-2