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Femtosecond laser-based nanosurgery reveals the endogenous regeneration of single Z-discs including physiological consequences for cardiomyocytes

A highly organized cytoskeleton architecture is the basis for continuous and controlled contraction in cardiomyocytes (CMs). Abnormalities in cytoskeletal elements, like the Z-disc, are linked to several diseases. It is challenging to reveal the mechanisms of CM failure, endogenous repair, or mechan...

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Detalles Bibliográficos
Autores principales: Müller, Dominik, Hagenah, Dorian, Biswanath, Santoshi, Coffee, Michelle, Kampmann, Andreas, Zweigerdt, Robert, Heisterkamp, Alexander, Kalies, Stefan M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403391/
https://www.ncbi.nlm.nih.gov/pubmed/30842507
http://dx.doi.org/10.1038/s41598-019-40308-z