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Details of hydrophobic entanglement between small molecules and Braun’s lipoprotein within the cavity of the bacterial chaperone LolA

The cell envelope of Gram-negative bacteria is synthesized and maintained via mechanisms that are targets for development of novel antibiotics. Here we focus on the process of moving Braun’s lipoprotein (BLP) from the periplasmic space to the outer membrane of E. coli, via the LolA protein. In contr...

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Detalles Bibliográficos
Autores principales: Boags, Alister, Samsudin, Firdaus, Khalid, Syma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403396/
https://www.ncbi.nlm.nih.gov/pubmed/30842499
http://dx.doi.org/10.1038/s41598-019-40170-z