Cyclosporin A ameliorates cerebral oxidative metabolism and infarct size in the endothelin-1 rat model of transient cerebral ischaemia

Cerebral microdialysis can be used to detect mitochondrial dysfunction, a potential target of neuroprotective treatment. Cyclosporin A (CsA) is a mitochondrial stabiliser that in a recent clinical stroke trial showed protective potential in patients with successful recanalisation. To investigate spe...

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Detalles Bibliográficos
Autores principales: Forsse, Axel, Nielsen, Troels Halfeld, Nygaard, Kevin Heebøll, Nordström, Carl-Henrik, Gramsbergen, Jan Bert, Poulsen, Frantz Rom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403404/
https://www.ncbi.nlm.nih.gov/pubmed/30842488
http://dx.doi.org/10.1038/s41598-019-40245-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403404/
https://www.ncbi.nlm.nih.gov/pubmed/30842488
http://dx.doi.org/10.1038/s41598-019-40245-x

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