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GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity

BACKGROUND AND AIMS: Platelets play a fundamental role in the increased atherothrombotic risk related to central obesity since they show hyperactivation and lower sensitivity to antiplatelet therapy in obese patients. The main goal of this study was to identify platelet biomarkers related to the ris...

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Detalles Bibliográficos
Autores principales: Barrachina, María N., Sueiro, Aurelio M., Izquierdo, Irene, Hermida-Nogueira, Lidia, Guitián, Esteban, Casanueva, Felipe F., Farndale, Richard W., Moroi, Masaaki, Jung, Stephanie M., Pardo, María, García, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403451/
https://www.ncbi.nlm.nih.gov/pubmed/30658193
http://dx.doi.org/10.1016/j.atherosclerosis.2018.12.023