Aberrant mRNA splicing generates oncogenic RNA isoforms and contributes to the development and progression of cholangiocarcinoma

Cholangiocarcinoma is a lethal biliary cancer, with an unclear molecular pathogenesis. Alternative splicing is a post-transcriptional modification that generates mature mRNAs, which are subsequently translated into proteins. Aberrant alternative splicing has been reported to serve a role in tumor in...

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Detalles Bibliográficos
Autores principales: Yosudjai, Juthamas, Wongkham, Sopit, Jirawatnotai, Siwanon, Kaewkong, Worasak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403481/
https://www.ncbi.nlm.nih.gov/pubmed/30906543
http://dx.doi.org/10.3892/br.2019.1188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403481/
https://www.ncbi.nlm.nih.gov/pubmed/30906543
http://dx.doi.org/10.3892/br.2019.1188

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