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Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk

BACKGROUND: Loss-of-function mutations in the SGLT1 (sodium/glucose co-transporter-1) gene result in a rare glucose/galactose malabsorption disorder and neonatal death if untreated. In the general population, variants related to intestinal glucose absorption remain uncharacterized. OBJECTIVES: The g...

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Detalles Bibliográficos
Autores principales: Seidelmann, Sara B., Feofanova, Elena, Yu, Bing, Franceschini, Nora, Claggett, Brian, Kuokkanen, Mikko, Puolijoki, Hannu, Ebeling, Tapani, Perola, Markus, Salomaa, Veikko, Shah, Amil, Coresh, Josef, Selvin, Elizabeth, MacRae, Calum A., Cheng, Susan, Boerwinkle, Eric, Solomon, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403489/
https://www.ncbi.nlm.nih.gov/pubmed/30286918
http://dx.doi.org/10.1016/j.jacc.2018.07.061