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Biodegradable Gene Carriers Containing Rigid Aromatic Linkage with Enhanced DNA Binding and Cell Uptake

The linking and modification of low molecular weight cationic polymers (oligomers) has become an attracted strategy to construct non-viral gene carriers with good transfection efficiency and much reduced cytotoxicity. In this study, PEI 600 Da was linked by biodegradable bridges containing rigid aro...

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Detalles Bibliográficos
Autores principales: Zhang, Ju-Hui, Yang, Hui-Zhen, Zhang, Ji, Liu, Yan-Hong, He, Xi, Xiao, Ya-Ping, Yu, Xiao-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403675/
https://www.ncbi.nlm.nih.gov/pubmed/30961005
http://dx.doi.org/10.3390/polym10101080