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Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine

RNA interference (RNAi), mediated by small interfering RNA (siRNA), has been considered as a potential therapeutic agent for cancer owing to its ability to suppress target genes in a sequence-specific manner. In this study, a conjugate of the low molecular weight (M(W)) polyethylenimine (PEI) (M(W)...

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Detalles Bibliográficos
Autores principales: Yin, Yue, Lee, Jung Eun, Kim, Nak Won, Lee, Jong Han, Lim, Su Yeon, Kim, E Seul, Park, Ji Won, Lee, Min Sang, Jeong, Ji Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403700/
https://www.ncbi.nlm.nih.gov/pubmed/30960878
http://dx.doi.org/10.3390/polym10090953