Single-Molecule Dynamics and Discrimination between Hydrophilic and Hydrophobic Amino Acids in Peptides, through Controllable, Stepwise Translocation across Nanopores

In this work, we demonstrate the proof-of-concept of real-time discrimination between patches of hydrophilic and hydrophobic monomers in the primary structure of custom-engineered, macro-dipole-like peptides, at uni-molecular level. We employed single-molecule recordings to examine the ionic current...

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Detalles Bibliográficos
Autores principales: Asandei, Alina, Dragomir, Isabela S., Di Muccio, Giovanni, Chinappi, Mauro, Park, Yoonkyung, Luchian, Tudor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403800/
https://www.ncbi.nlm.nih.gov/pubmed/30960810
http://dx.doi.org/10.3390/polym10080885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403800/
https://www.ncbi.nlm.nih.gov/pubmed/30960810
http://dx.doi.org/10.3390/polym10080885

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