Design, Synthesis, and Characterization of Schiff Base Bond-Linked pH-Responsive Doxorubicin Prodrug Based on Functionalized mPEG-PCL for Targeted Cancer Therapy

The side effects of doxorubicin (DOX) extremely limit its application in the treatment of malignant tumors. Nano-sized polymeric drugs based on the acidic microenvironment of tissular- or intra- tumor have attracted ample attention because of their potential in reducing side effects. In this researc...

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Detalles Bibliográficos
Autores principales: Zhai, Yinglei, Zhou, Xing, Zhang, Zhiqiang, Zhang, Lei, Wang, Dianyu, Wang, Xinhui, Sun, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404085/
https://www.ncbi.nlm.nih.gov/pubmed/30961052
http://dx.doi.org/10.3390/polym10101127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404085/
https://www.ncbi.nlm.nih.gov/pubmed/30961052
http://dx.doi.org/10.3390/polym10101127

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