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Chiral Discrimination of DL-Amino Acids by Trapped Ion Mobility Spectrometry after Derivatization with (+)-1-(9-Fluorenyl)ethyl Chloroformate

[Image: see text] A novel analytical method based on hybrid trapped ion mobility spectrometry-time-of-flight mass spectrometry (TIMS-TOFMS) has been developed to achieve fast enantiomeric separation of amino acids (AAs). Resolution of chiral AAs was achieved by forming diastereomers through derivati...

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Detalles Bibliográficos
Autores principales: Pérez-Míguez, Raquel, Bruyneel, Ben, Castro-Puyana, María, Marina, María Luisa, Somsen, Govert W., Domínguez-Vega, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404107/
https://www.ncbi.nlm.nih.gov/pubmed/30682252
http://dx.doi.org/10.1021/acs.analchem.8b03661