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Computational fluid dynamic analysis of physical forces playing a role in brain organoid cultures in two different multiplex platforms

BACKGROUND: Organoid cultivation in suspension culture requires agitation at low shear stress to allow for nutrient diffusion, which preserves tissue structure. Multiplex systems for organoid cultivation have been proposed, but whether they meet similar shear stress parameters as the regularly used...

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Detalles Bibliográficos
Autores principales: Goto-Silva, Livia, Ayad, Nadia M. E., Herzog, Iasmin L., Silva, Nilton P., Lamien, Bernard, Orlande, Helcio R. B., da Costa Souza, Annie, Ribeiro, Sidarta, Martins, Michele, Domont, Gilberto B., Junqueira, Magno, Tovar-Moll, Fernanda, Rehen, Stevens K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404276/
https://www.ncbi.nlm.nih.gov/pubmed/30841924
http://dx.doi.org/10.1186/s12861-019-0183-y