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Radiotherapy enhances responses of lung cancer to CTLA-4 blockade

Formenti et al. have recently reported the clinical outcomes and translational readouts of a trial of the anti-CTLA-4 inhibitor, ipilimumab, in combination with palliative radiotherapy in 39 patients with non-small cell lung cancer. A radiological response was seen in 18% of patients and 31% of pati...

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Detalles Bibliográficos
Autores principales: Wilkins, Anna, McDonald, Fiona, Harrington, Kevin, Melcher, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404307/
https://www.ncbi.nlm.nih.gov/pubmed/30841910
http://dx.doi.org/10.1186/s40425-019-0542-z