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In-depth characterization of the Wnt-signaling/β-catenin pathway in an in vitro model of Barrett’s sequence
BACKGROUND: An altered Wnt-signaling activation has been reported during Barrett’s esophagus progression, but with rarely detected mutations in APC and β-catenin (CTNNB1) genes. METHODS: In this study, a robust in-depth expression pattern analysis of frizzled receptors, co-receptors, the Wnt-ligands...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404335/ https://www.ncbi.nlm.nih.gov/pubmed/30841855 http://dx.doi.org/10.1186/s12876-019-0957-5 |