Human three-dimensional in vitro model of hepatic zonation to predict zonal hepatotoxicity

BACKGROUND: Various hepatic models mimicking liver lobules have been investigated to evaluate the potential hepatotoxic effects of chemicals and drugs, but in vitro hepatic models of zonal hepatotoxicity have not yet been established. Herein, we developed a three-dimensional (3D) hepatic zonal chann...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahn, Jaehwan, Ahn, Jun-Ho, Yoon, Seokjoo, Nam, Yoon Sung, Son, Mi-Young, Oh, Jung-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404355/
https://www.ncbi.nlm.nih.gov/pubmed/30886645
http://dx.doi.org/10.1186/s13036-019-0148-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404355/
https://www.ncbi.nlm.nih.gov/pubmed/30886645
http://dx.doi.org/10.1186/s13036-019-0148-5

Ejemplares similares