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Human three-dimensional in vitro model of hepatic zonation to predict zonal hepatotoxicity
BACKGROUND: Various hepatic models mimicking liver lobules have been investigated to evaluate the potential hepatotoxic effects of chemicals and drugs, but in vitro hepatic models of zonal hepatotoxicity have not yet been established. Herein, we developed a three-dimensional (3D) hepatic zonal chann...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404355/ https://www.ncbi.nlm.nih.gov/pubmed/30886645 http://dx.doi.org/10.1186/s13036-019-0148-5 |