Modular Synthesis of Bioreducible Gene Vectors through Polyaddition of N,N′-Dimethylcystamine and Diglycidyl Ethers

Bioreducible, cationic linear poly(amino ether)s (PAEs) were designed as promising gene vectors. These polymers were synthesized by the reaction of a disulfide-functional monomer, N,N′-dimethylcystamine (DMC), and several different diglycidyl ethers. The resulting PAEs displayed a substantial buffer...

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Detalles Bibliográficos
Autores principales: Si, Guoying, Elzes, M. Rachèl, Engbersen, Johan F. J., Paulusse, Jos M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404356/
https://www.ncbi.nlm.nih.gov/pubmed/30966721
http://dx.doi.org/10.3390/polym10060687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404356/
https://www.ncbi.nlm.nih.gov/pubmed/30966721
http://dx.doi.org/10.3390/polym10060687

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