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CRISPR: a new principle of genome engineering linked to conceptual shifts in evolutionary biology
The CRISPR-Cas systems of bacterial and archaeal adaptive immunity have become a household name among biologists and even the general public thanks to the unprecedented success of the new generation of genome editing tools utilizing Cas proteins. However, the fundamental biological features of CRISP...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404382/ https://www.ncbi.nlm.nih.gov/pubmed/30930513 http://dx.doi.org/10.1007/s10539-018-9658-7 |