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Thiol-free chemoenzymatic synthesis of β-ketosulfides

A preparation of β-ketosulfides avoiding the use of thiols is described. The combination of a multicomponent reaction and a lipase-catalysed hydrolysis has been developed in order to obtain high chemical diversity employing a single sulfur donor. This methodology for the selective synthesis of a set...

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Detalles Bibliográficos
Autores principales: Heredia, Adrián A, López-Vidal, Martín G, Kurina-Sanz, Marcela, Bisogno, Fabricio R, Peñéñory, Alicia B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404416/
https://www.ncbi.nlm.nih.gov/pubmed/30873224
http://dx.doi.org/10.3762/bjoc.15.34