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Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila

The repeated and improper use of antibiotics had led to an increased number of multiresistant bacteria. Therefore, new lead structures are needed. Here, the synthesis and an expanded structure–activity relationship of the simple and antistaphylococcal amide nematophin from Xenorhabdus nematophila an...

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Detalles Bibliográficos
Autores principales: Wesche, Frank, Adihou, Hélène, Wichelhaus, Thomas A, Bode, Helge B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404511/
https://www.ncbi.nlm.nih.gov/pubmed/30873237
http://dx.doi.org/10.3762/bjoc.15.47