Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration

Staphylococcus aureus Panton-Valentine leukocidin is a pore-forming toxin targeting the human C5a receptor (hC5aR), enabling this pathogen to battle the immune response by destroying phagocytes through targeted lysis. The mechanisms that contribute to rapid cell lysis are largely unexplored. Here, w...

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Detalles Bibliográficos
Autores principales: Haapasalo, Karita, Wollman, Adam J. M., de Haas, Carla J. C., van Kessel, Kok P. M., van Strijp, Jos A. G., Leake, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404581/
https://www.ncbi.nlm.nih.gov/pubmed/30509126
http://dx.doi.org/10.1096/fj.201801910R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404581/
https://www.ncbi.nlm.nih.gov/pubmed/30509126
http://dx.doi.org/10.1096/fj.201801910R

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