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Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration
Staphylococcus aureus Panton-Valentine leukocidin is a pore-forming toxin targeting the human C5a receptor (hC5aR), enabling this pathogen to battle the immune response by destroying phagocytes through targeted lysis. The mechanisms that contribute to rapid cell lysis are largely unexplored. Here, w...
Autores principales: | Haapasalo, Karita, Wollman, Adam J. M., de Haas, Carla J. C., van Kessel, Kok P. M., van Strijp, Jos A. G., Leake, Mark C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404581/ https://www.ncbi.nlm.nih.gov/pubmed/30509126 http://dx.doi.org/10.1096/fj.201801910R |
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