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polyRAD: Genotype Calling with Uncertainty from Sequencing Data in Polyploids and Diploids

Low or uneven read depth is a common limitation of genotyping-by-sequencing (GBS) and restriction site-associated DNA sequencing (RAD-seq), resulting in high missing data rates, heterozygotes miscalled as homozygotes, and uncertainty of allele copy number in heterozygous polyploids. Bayesian genotyp...

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Detalles Bibliográficos
Autores principales: Clark, Lindsay V., Lipka, Alexander E., Sacks, Erik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404598/
https://www.ncbi.nlm.nih.gov/pubmed/30655271
http://dx.doi.org/10.1534/g3.118.200913