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Coverage-Versus-Length Plots, a Simple Quality Control Step for de Novo Yeast Genome Sequence Assemblies

Illumina sequencing has revolutionized yeast genomics, with prices for commercial draft genome sequencing now below $200. The popular SPAdes assembler makes it simple to generate a de novo genome assembly for any yeast species. However, whereas making genome assemblies has become routine, understand...

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Detalles Bibliográficos
Autores principales: Douglass, Alexander P., O’Brien, Caoimhe E., Offei, Benjamin, Coughlan, Aisling Y., Ortiz-Merino, Raúl A., Butler, Geraldine, Byrne, Kevin P., Wolfe, Kenneth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404606/
https://www.ncbi.nlm.nih.gov/pubmed/30674538
http://dx.doi.org/10.1534/g3.118.200745