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Preparation, intestinal segment stability, and mucoadhesion properties of novel thymopentin-loaded chitosan derivatives coated with poly (n-butyl) cyanoacrylate nanoparticles

BACKGROUND: In order to develop a promising carrier for the oral delivery of proteins and peptide drugs, a novel bioadhesive nanocarrier of chitosan (CTS) derivatives coated with poly (n-butyl) cyanoacrylate nanoparticles (PBCA-NPs) was prepared in this study. METHODS: Three different thymopentin (T...

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Detalles Bibliográficos
Autores principales: Xu, Ying, Lu, Shengzhe, Liu, Qi, Hong, Yun, Xu, Bohui, Ping, Qineng, Jin, Xuefeng, Shen, Yan, Webster, Thomas J, Rao, Yuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404670/
https://www.ncbi.nlm.nih.gov/pubmed/30880971
http://dx.doi.org/10.2147/IJN.S194529