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Preparation, intestinal segment stability, and mucoadhesion properties of novel thymopentin-loaded chitosan derivatives coated with poly (n-butyl) cyanoacrylate nanoparticles
BACKGROUND: In order to develop a promising carrier for the oral delivery of proteins and peptide drugs, a novel bioadhesive nanocarrier of chitosan (CTS) derivatives coated with poly (n-butyl) cyanoacrylate nanoparticles (PBCA-NPs) was prepared in this study. METHODS: Three different thymopentin (T...
Autores principales: | Xu, Ying, Lu, Shengzhe, Liu, Qi, Hong, Yun, Xu, Bohui, Ping, Qineng, Jin, Xuefeng, Shen, Yan, Webster, Thomas J, Rao, Yuefeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404670/ https://www.ncbi.nlm.nih.gov/pubmed/30880971 http://dx.doi.org/10.2147/IJN.S194529 |
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