Resveratrol inhibits paclitaxel-induced neuropathic pain by the activation of PI3K/Akt and SIRT1/PGC1α pathway

BACKGROUND: Phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) is one of the essential signaling pathways for the development and maintenance of neuropathic pain. OBJECTIVE: To investigate the effect of resveratrol (RES) on paclitaxel-induced neuropathic pain in rats and elucidate the underlyin...

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Detalles Bibliográficos
Autores principales: Li, Xiaoning, Yang, Shuhong, Wang, Liang, Liu, Peng, Zhao, Shuang, Li, Huizhou, Jiang, Yuqing, Guo, Yuexian, Wang, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404678/
https://www.ncbi.nlm.nih.gov/pubmed/30881098
http://dx.doi.org/10.2147/JPR.S185873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404678/
https://www.ncbi.nlm.nih.gov/pubmed/30881098
http://dx.doi.org/10.2147/JPR.S185873

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