Single-Cell Approach to Monitor the Unfolded Protein Response During Biotechnological Processes With Pichia pastoris

Pichia pastoris (Komagataella sp.) is broadly used for the production of secreted recombinant proteins. Due to the high rate of protein production, incorrectly folded proteins may accumulate in the endoplasmic reticulum (ER). To restore their proper folding, the cell triggers the unfolded protein re...

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Detalles Bibliográficos
Autores principales: Raschmanová, Hana, Zamora, Iwo, Borčinová, Martina, Meier, Patrick, Weninger, Astrid, Mächler, Dominik, Glieder, Anton, Melzoch, Karel, Knejzlík, Zdeněk, Kovar, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404689/
https://www.ncbi.nlm.nih.gov/pubmed/30873140
http://dx.doi.org/10.3389/fmicb.2019.00335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404689/
https://www.ncbi.nlm.nih.gov/pubmed/30873140
http://dx.doi.org/10.3389/fmicb.2019.00335

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