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Coronary Endothelial Dysfunction Is Associated With Elevated Serum PCSK9 Levels in People With HIV Independent of Low‐Density Lipoprotein Cholesterol

BACKGROUND: HIV+ people are at increased risk of coronary artery disease, but the responsible mechanisms are incompletely understood. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is traditionally recognized for its importance in cholesterol metabolism; however, recent data suggest an additi...

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Detalles Bibliográficos
Autores principales: Leucker, Thorsten M., Weiss, Robert G., Schär, Michael, Bonanno, Gabriele, Mathews, Lena, Jones, Steven R., Brown, Todd T., Moore, Richard, Afework, Yohannes, Gerstenblith, Gary, Hays, Allison G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404863/
https://www.ncbi.nlm.nih.gov/pubmed/30371326
http://dx.doi.org/10.1161/JAHA.118.009996