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Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts

BACKGROUND: Dilated cardiomyopathy (DCM) is a common cause of heart failure in adult and pediatric patients, but the underlying mechanism may vary in adults and children, with few studies conducted to date. The objective of the present study was to determine whether differential remodeling of the ex...

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Detalles Bibliográficos
Autores principales: Jana, Sayantan, Zhang, Hao, Lopaschuk, Gary D., Freed, Darren H., Sergi, Consolato, Kantor, Paul F., Oudit, Gavin Y., Kassiri, Zamaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404896/
https://www.ncbi.nlm.nih.gov/pubmed/30371322
http://dx.doi.org/10.1161/JAHA.118.010427