Varying label density allows artifact-free analysis of membrane-protein nanoclusters

We present a new method to robustly discriminate clustered from random distributions of molecules detected with single molecule localization microscopy-based techniques like PALM and STORM. The approach is based on the deliberate variation of the labeling density, e.g. by titration of fluorescent an...

Descripción completa

Detalles Bibliográficos
Autores principales: Baumgart, Florian, Arnold, Andreas, Leskovar, Konrad, Staszek, Kaj, Fölser, Martin, Weghuber, Julian, Stockinger, Hannes, Schütz, Gerhard. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404959/
https://www.ncbi.nlm.nih.gov/pubmed/27295310
http://dx.doi.org/10.1038/nmeth.3897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404959/
https://www.ncbi.nlm.nih.gov/pubmed/27295310
http://dx.doi.org/10.1038/nmeth.3897

Ejemplares similares