Cargando…
Varying label density allows artifact-free analysis of membrane-protein nanoclusters
We present a new method to robustly discriminate clustered from random distributions of molecules detected with single molecule localization microscopy-based techniques like PALM and STORM. The approach is based on the deliberate variation of the labeling density, e.g. by titration of fluorescent an...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404959/ https://www.ncbi.nlm.nih.gov/pubmed/27295310 http://dx.doi.org/10.1038/nmeth.3897 |