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Intraperitoneal aerosolization of albumin-stabilized paclitaxel nanoparticles (Abraxane™) for peritoneal carcinomatosis – a phase I first-in-human study

BACKGROUND: Nanoparticles hold considerable promise for aerosol-based intraperitoneal delivery in patients with carcinomatosis. Recently, results from preclinical and early clinical trials suggested that albumin-bound paclitaxel (ABP, Abraxane™) may result in superior efficacy in the treatment of pe...

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Detalles Bibliográficos
Autores principales: Van De Sande, Leen, Graversen, Martin, Hubner, Martin, Pocard, Marc, Reymond, Marc, Vaira, Marco, Cosyns, Sarah, Willaert, Wouter, Ceelen, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405003/
https://www.ncbi.nlm.nih.gov/pubmed/30911657
http://dx.doi.org/10.1515/pp-2018-0112