Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization

The intestinal microbiota influences the development and function of myeloid lineages such as neutrophils, but the underlying molecular mechanisms are unresolved. Using gnotobiotic zebrafish, we identified the immune effector Serum amyloid A (Saa) as one of the most highly induced transcripts in dig...

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Detalles Bibliográficos
Autores principales: Murdoch, Caitlin C., Espenschied, Scott T., Matty, Molly A., Mueller, Olaf, Tobin, David M., Rawls, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405052/
https://www.ncbi.nlm.nih.gov/pubmed/30845179
http://dx.doi.org/10.1371/journal.ppat.1007381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405052/
https://www.ncbi.nlm.nih.gov/pubmed/30845179
http://dx.doi.org/10.1371/journal.ppat.1007381

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