Cargando…
Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization
The intestinal microbiota influences the development and function of myeloid lineages such as neutrophils, but the underlying molecular mechanisms are unresolved. Using gnotobiotic zebrafish, we identified the immune effector Serum amyloid A (Saa) as one of the most highly induced transcripts in dig...
Autores principales: | Murdoch, Caitlin C., Espenschied, Scott T., Matty, Molly A., Mueller, Olaf, Tobin, David M., Rawls, John F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405052/ https://www.ncbi.nlm.nih.gov/pubmed/30845179 http://dx.doi.org/10.1371/journal.ppat.1007381 |
Ejemplares similares
-
An Explant Technique for High-Resolution Imaging and Manipulation of Mycobacterial Granulomas
por: Cronan, Mark R., et al.
Publicado: (2018) -
Commensal Microbiota Regulate Vertebrate Innate Immunity-Insights From the Zebrafish
por: Murdoch, Caitlin C., et al.
Publicado: (2019) -
CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation
por: Wang, Liuyang, et al.
Publicado: (2015) -
Glycine induces enhancement of bactericidal activity of neutrophils
por: Kang, Shin-Hae, et al.
Publicado: (2022) -
Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils
por: Margaroli, Camilla, et al.
Publicado: (2021)