Arginase-II negatively regulates renal aquaporin-2 and water reabsorption

Type-II l-arginine:ureahydrolase, arginase-II (Arg-II), is abundantly expressed in the kidney. The physiologic role played by Arg-II in the kidney remains unknown. Herein, we report that in mice that are deficient in Arg-II (Arg-II(−/−)), total and membrane-associated aquaporin-2 (AQP2) protein leve...

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Detalles Bibliográficos
Autores principales: Huang, Ji, Montani, Jean-Pierre, Verrey, François, Feraille, Eric, Ming, Xiu-Fen, Yang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405175/
https://www.ncbi.nlm.nih.gov/pubmed/29718707
http://dx.doi.org/10.1096/fj.201701209R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405175/
https://www.ncbi.nlm.nih.gov/pubmed/29718707
http://dx.doi.org/10.1096/fj.201701209R

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