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Arginase-II negatively regulates renal aquaporin-2 and water reabsorption
Type-II l-arginine:ureahydrolase, arginase-II (Arg-II), is abundantly expressed in the kidney. The physiologic role played by Arg-II in the kidney remains unknown. Herein, we report that in mice that are deficient in Arg-II (Arg-II(−/−)), total and membrane-associated aquaporin-2 (AQP2) protein leve...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Federation of American Societies for Experimental
Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405175/ https://www.ncbi.nlm.nih.gov/pubmed/29718707 http://dx.doi.org/10.1096/fj.201701209R |