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Nanobody immunostaining for correlated light and electron microscopy with preservation of ultrastructure

Morphological and molecular characteristics determine the function of biological tissues. Attempts to combine immunofluorescence and electron microscopy invariably compromise the quality of the ultrastructure of tissue sections. We developed NATIVE, a correlated light and electron microscopy approac...

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Detalles Bibliográficos
Autores principales: Fang, Tao, Lu, Xiaotang, Berger, Daniel, Gmeiner, Christina, Cho, Julia, Schalek, Richard, Ploegh, Hidde, Lichtman, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405223/
https://www.ncbi.nlm.nih.gov/pubmed/30397326
http://dx.doi.org/10.1038/s41592-018-0177-x