KLF4, A Gene Regulating Prostate Stem Cell Homeostasis, Is a Barrier to Malignant Progression and Predictor of Good Prognosis in Prostate Cancer

There is a considerable need to identify those individuals with prostate cancer who have indolent disease. We propose that genes that control adult stem cell homeostasis in organs with slow turnover, such as the prostate, control cancer fate. One such gene, KLF4, overexpressed in murine prostate ste...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Xiaozhong, Schober, Markus, Tassone, Evelyne, Khodadadi-Jamayran, Alireza, Sastre-Perona, Ana, Zhou, Hua, Tsirigos, Aristotelis, Shen, Steven, Chang, Miao, Melamed, Jonathan, Ossowski, Liliana, Wilson, Elaine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405286/
https://www.ncbi.nlm.nih.gov/pubmed/30540935
http://dx.doi.org/10.1016/j.celrep.2018.11.065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405286/
https://www.ncbi.nlm.nih.gov/pubmed/30540935
http://dx.doi.org/10.1016/j.celrep.2018.11.065

Ejemplares similares