Perampanel Affects Up-Stream Regulatory Signaling Pathways of GluA1 Phosphorylation in Normal and Epileptic Rats

To elucidate the pharmacological properties of perampanel [2-(2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile, a novel non-competitive antagonist of AMPA receptor], we investigated its effects on the up-stream regulatory pathways of GluA1 phosphorylation including protein kinase C...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Choi, Hui-Chul, Song, Hong-Ki, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405474/
https://www.ncbi.nlm.nih.gov/pubmed/30881292
http://dx.doi.org/10.3389/fncel.2019.00080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405474/
https://www.ncbi.nlm.nih.gov/pubmed/30881292
http://dx.doi.org/10.3389/fncel.2019.00080

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