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Identification of Important Effector Proteins in the FOXJ1 Transcriptional Network Associated With Ciliogenesis and Ciliary Function

Developmental defects in motile cilia, arising from genetic abnormalities in one or more ciliary genes, can lead to a common ciliopathy known as primary ciliary dyskinesia (PCD). Functional studies in model organisms undertaken to understand PCD or cilia biogenesis have identified 100s of genes regu...

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Detalles Bibliográficos
Autores principales: Mukherjee, Ishita, Roy, Sudipto, Chakrabarti, Saikat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405523/
https://www.ncbi.nlm.nih.gov/pubmed/30881373
http://dx.doi.org/10.3389/fgene.2019.00023