Caspase Cleavage of Gelsolin Is an Inductive Cue for Pathologic Cardiac Hypertrophy

BACKGROUND: Cardiac hypertrophy is an adaptive remodeling event that may improve or diminish contractile performance of the heart. Physiologic and pathologic hypertrophy yield distinct outcomes, yet both are dependent on caspase‐directed proteolysis. This suggests that each form of myocardial growth...

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Detalles Bibliográficos
Autores principales: Putinski, Charis, Abdul‐Ghani, Mohammad, Brunette, Steve, Burgon, Patrick G., Megeney, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405540/
https://www.ncbi.nlm.nih.gov/pubmed/30486716
http://dx.doi.org/10.1161/JAHA.118.010404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405540/
https://www.ncbi.nlm.nih.gov/pubmed/30486716
http://dx.doi.org/10.1161/JAHA.118.010404

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