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CD40L Priming of Platelets via NF‐κB Activation is CD40‐ and TAK1‐Dependent

BACKGROUND: CD40 ligand (CD40L) is a thromboinflammatory molecule that predicts cardiovascular events. CD40L is a strong activator of nuclear factor kappa B (NF‐κB) in platelets that primes and enhances platelet activation in response to thrombotic stimuli. In addition to its classical receptor CD40...

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Detalles Bibliográficos
Autores principales: Kojok, Kevin, Akoum, Souhad El, Mohsen, Mira, Mourad, Walid, Merhi, Yahye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405550/
https://www.ncbi.nlm.nih.gov/pubmed/30571597
http://dx.doi.org/10.1161/JAHA.118.009636