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Increased Vulnerability to Atrial Fibrillation Is Associated With Increased Susceptibility to Alternans in Old Sheep

BACKGROUND: Atrial fibrillation (AF) is common in the elderly, but rare in the young; however, the changes that occur with age that promote AF are not fully understood. Action potential (AP) alternans may be involved in the initiation of AF. Using a translationally relevant model, we investigated wh...

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Detalles Bibliográficos
Autores principales: Pearman, Charles M., Madders, George W.P., Radcliffe, Emma J., Kirkwood, Graeme J., Lawless, Michael, Watkins, Amy, Smith, Charlotte E.R., Trafford, Andrew W., Eisner, David A., Dibb, Katharine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405564/
https://www.ncbi.nlm.nih.gov/pubmed/30520673
http://dx.doi.org/10.1161/JAHA.118.009972