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Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy

BACKGROUND: Sustained pressure overload leads to changes in cardiac metabolism, function, and structure. Both time course and causal relationships between these changes are not fully understood. Therefore, we studied spontaneously hypertensive rats (SHR) during early hypertension development and com...

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Detalles Bibliográficos
Autores principales: Li, Jie, Kemp, Brandon A., Howell, Nancy L., Massey, James, Mińczuk, Krzysztof, Huang, Qiao, Chordia, Mahendra D., Roy, R. Jack, Patrie, James T., Davogustto, Giovanni E., Kramer, Christopher M., Epstein, Frederick H., Carey, Robert M., Taegtmeyer, Heinrich, Keller, Susanna R., Kundu, Bijoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405673/
https://www.ncbi.nlm.nih.gov/pubmed/30764689
http://dx.doi.org/10.1161/JAHA.118.010926