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Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy
BACKGROUND: Sustained pressure overload leads to changes in cardiac metabolism, function, and structure. Both time course and causal relationships between these changes are not fully understood. Therefore, we studied spontaneously hypertensive rats (SHR) during early hypertension development and com...
Autores principales: | Li, Jie, Kemp, Brandon A., Howell, Nancy L., Massey, James, Mińczuk, Krzysztof, Huang, Qiao, Chordia, Mahendra D., Roy, R. Jack, Patrie, James T., Davogustto, Giovanni E., Kramer, Christopher M., Epstein, Frederick H., Carey, Robert M., Taegtmeyer, Heinrich, Keller, Susanna R., Kundu, Bijoy K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405673/ https://www.ncbi.nlm.nih.gov/pubmed/30764689 http://dx.doi.org/10.1161/JAHA.118.010926 |
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