Promotion or Suppression of Murine Intestinal Polyp Development by iNKT Cell Directed Immunotherapy

The glycosphingolipid α-galactosylceramide (α-GalCer) is a well-described immune activator with strong anti-tumor properties in animal models. It is presented on CD1d and acts by stimulating the invariant, type I, natural killer T (iNKT) lymphocytes to rapidly secrete TH1 and TH2 associated cytokine...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Sedimbi, Saikiran K., Löfbom, Linda, Besra, Gurdyal S., Porcelli, Steven A., Cardell, Susanna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405695/
https://www.ncbi.nlm.nih.gov/pubmed/30881361
http://dx.doi.org/10.3389/fimmu.2019.00352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405695/
https://www.ncbi.nlm.nih.gov/pubmed/30881361
http://dx.doi.org/10.3389/fimmu.2019.00352

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