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New Molecular Mechanism Underlying Myc‐Mediated Cytochrome P450 2E1 Upregulation in Apoptosis and Energy Metabolism in the Myocardium

BACKGROUND: Canonical studies indicate that cytochrome P450 2E1 (CYP2E1) plays a critical role in the metabolism of xenobiotics and ultimately participates in tissue damage. CYP2E1 upregulates in the pathophysiological development of multiple diseases; however, the mechanism of CYP2E1 upregulation,...

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Detalles Bibliográficos
Autores principales: Guan, Feifei, Yang, Xinlan, Li, Jing, Dong, Wei, Zhang, Xu, Liu, Ning, Gao, Shan, Wang, Jizheng, Zhang, Lianfeng, Lu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405704/
https://www.ncbi.nlm.nih.gov/pubmed/30563421
http://dx.doi.org/10.1161/JAHA.118.009871